<p>Effective method of evaluating myocardial iron concentration in pediatric patients with thalassemia major</p>
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چکیده
منابع مشابه
Association between serum ferritin and liver iron concentration with cardiac iron in pediatric thalassemia major patients
Background Recently, the ability of LIC (liver iron concentration) and serum ferritin in predicting myocardial iron overload (MIO) has been challenged by magnetic Resonance Imaging (MRI) monitoring which demonstrated no or weak correlation between serum ferritin or LIC and MIO. Anyway, the role of this traditional markers could result particularly useful in pediatric population, where MRI asses...
متن کاملAn automatic method for myocardial T2* curve fitting in thalassemia patients with severe iron overload
Background Myocardial iron overload assessment by multislice multiecho T2* technique is used in the clinical management of thalassemia major (TM) patients. Signal decay curves are extracted from the 16 left ventricular (LV) segments and the fitting of these curves to a mono-exponential model provides the corresponding T2* values. In patients with severe cardiac iron overload, where signal will ...
متن کاملEndocrine Dysfunctions in Iron Overload in Patients with Major Thalassemia
Abstract Background The aim of the present study was to determine the endocrine dysfunction in patients with major thalassemia, who receive hyper transfusion. Materials and Methods This cross sectional study was performed during one year, which included 65 major thalassemia patients (31 females and 34 males), aged between 14 month to 27 years old (median 10,3). Growth assessment was measur...
متن کاملMyocardial iron overload in sickle/thalassemia patients of Italian origin
Background Sickle-thalassemia is an inherited hemoglobin disorder resulting from the combined heterozygosity for sicklecell and b-thalassemia genes. Myocardial iron overload in patients with sickle-thalassemia has been poorly studied; however, a report has shown no evidence of cardiac iron in a small group (n=10) of multitransfused Arab patients. The current study aims to further evaluate cardi...
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ژورنال
عنوان ژورنال: Journal of Blood Medicine
سال: 2019
ISSN: 1179-2736
DOI: 10.2147/jbm.s204848